LaVoieHealthScience Announces New PR Clients to its Roster

BOSTON, MA – March 23, 2017 – LaVoieHealthScience (LHS), an integrated investor and public relations agency focused on advancing health and science innovations, today announced it has signed new clients to its public relations client roster including BioAxone BioSciences, Inc.,

 “Our passion is to represent true innovators in the health and science fields,” said Donna L. LaVoie, President and CEO, LaVoieHealthScience.  “Our client companies are led by scientific and business visionaries who are shaping the way patients will be treated and making difference in healthcare delivery. We are delighted to expand our reach in biotechnology, medical device, and medical technology.” 

LaVoieHealthScience is leading a full array of integrated communications for these new clients including LHS Immersion®, The LHS Fifteen Slide Presentation®,  investor and corporate communications, investor and business development access, local and national media relations, digital and content development, thought leadership as well as social engagement programs.  The companies’ expertise includes:

  • BioAxone BioSciences, Cambridge, MA is committed to applying a deep understanding of  axon regeneration and neuronal signaling pathways to transform the lives of patients afflicted with neurotrauma or neurovascular disorder.
  • MicroPort Orthopedics, Burlington, MA,  is a medical device company that develops and manufactures knee and hip implants designed to help patients achieve full function faster. 
  • Major global pharmaceutical company, Cambridge MA, is exploring cutting-edge science and technology opportunities with relevance for dermatology.

About LaVoieHealthScience
LaVoieHealthScience partners with leading life science brands to build value for their companies, attract capital and reach key stakeholders through integrated communications and marketing. The firm provides strategic communications, investor relations and public relations to build recognition and increase sales and value for health science innovations. The agency has received 28 awards over the past seven years in recognition of the work it has done for its health and science industry-leading clients.  In addition to clients listed above, LaVoieHealthScience represents leaders such as Cydan Development, Imara, NewLink Genetics, Biotechnology Innovation Organization, Newron Pharmaceuticals, Origenis, and other emerging health and science companies.

Contact:
Beth Kurth
Vice President, Investor Relations
LaVoieHealthScience
bkurth@lavoiehealthscience.com
617 374 8800, x106

Spotlight: Q&A with Michael Almstetter, CEO, Origenis

Michael Almstetter

CEO

Q: What does Origenis do?
A: Origenis is creating small molecule drugs capable of penetrating the blood-brain barrier and therefore treating neurodegenerative diseases – commonly known as Central Nervous System, or CNS, diseases. Our technology-based drug design process develops faster, more specific compounds. I am pleased to note our platform has been validated through internal projects and external partners, and has yielded several patented drug candidates now in late stage clinical development since its application in 2005.

Q: What was your inspiration for founding Origenis? What do you hope to achieve?
A: Our goal is to fight neurodegeneration by breaking the vicious cycle that contributes to CNS diseases. That cycle includes microglia activation, which leads to neuro-inflammation, and then cell death, in turn contributing to microglia activation and so on. By inhibiting any of these phases of the cycle, Origenis can help regarding several chronic and acute neurodegenerative diseases such as Parkinson’s Disease, Alzheimer’s, dementia and Multiple Sclerosis as well as Traumatic Brain Injury and Hypoxic-Ischemic Encephalopathy.

Q: How does Origenis’ drug discovery platform work?
A: Origenis drug discovery platform has four major pillars: MOREsystem®, MolMind®, and Cippix® represent the proprietary technologies for the fast identification, seamless optimization and efficient synthesis of patentable new chemical entities. The pharmacological efficacy of our compounds is assessed and optimized with BRAINstorm™, the key technology for generating and optimizing brain penetrating compounds at Origenis.

Q: Sounds interesting, is there a competitive advantage?
A: Absolutely! With our leveraging unique chemistry capabilities we provide continual IP-protected new chemical entities. Our unique drug discovery process allows a faster and more specific development of compounds and delivers de-risked new chemical entities for partners, and of course for ourselves. As noted earlier, our platform has been validated not only through internal projects, but also with external partners and has yielded several patented drug candidates.

Q: Can you give us insight into current projects?
A: Origenis develops several, distinct small molecule drugs, which nicely cross the blood brain barrier with no need for a special formulation. These drugs act highly specifically on selected protein kinases responsible for microglia activation, neuronal cell death and neuroinflammation.

Our front-runner is our LRRK2 (Leucine Rich Repeat Kinase 2) therapeutic program. Inhibition of LRRK2 results in a significant decrease in neuronal damage. This opens the avenue for a first disease-modifying treatment in the field of Parkinson’s disease. Our LRRK2 lead drug candidate has outstanding compound properties in terms of potency and selectivity and an execellent brain penetration and PK profle. It should be mentioned that we were the first company to show in-vivo efficacy in an acute neuroegeneration model with our brain available LRRK2 inhibitor.

In addition to the therapeutic programs, Origenis also develops specific PET tracers – necessary tools to translate preclinical compounds into clinical drugs. These PET tracers are a huge strategic advantage in this highly competitive field. Origenis 18F-radiolabelled LRRK2-specific PET tracer, the only one available in the world. This represents the key differentiator in the LRRK2 field and opens a range of partnering and licensing options.

Q: Why is there so much excitement about LRRK2?
A: Two words: science and impact. There is now a deeper understanding of the science and a broader understanding of the impact. In terms of science, a mutation in LRRK2 has been identified as a genetic marker for Parkinson’s disease. In terms of the impact, we have people like Michael J. Fox who has the disease, and Google co-founder Sergey Brin who has the marker. Thus there is more interest from foundations, big pharma and others.

Q: Who else is on the Origenis leadership team?
A: Origenis was founded in 2005 by Michael Thormann, CSO, Andreas Treml, COO and myself. We previously worked together at a multinational biotech company, developing technologies and functioning as a business unit. We have a proven track record in drug design, compound synthesis and characterization. We are based in Munich, Germany and recently added CFO Thomas Loeser who brings financial and deal making expertise, in both Europe and the U.S.

Q: What is Origenis’ business strategy going forward?
A: Since we are already established as an R&D partner of choice, we have a track record of steady and profitable growth of R&D collaborations. That being said, we extended our business model towards faster value creation and are currently seeking up to €20 million for Series A financing to advance our internal pipeline.

We have full ownership of all projects, results and data packages. Our partnering strategy entails out-licensing assets from our significant IP and R&D portfolio and building partnering agreements with large pharmaceutical companies.

LaVoieHealthScience Awarded MarCom Gold for Oticon Opn™ Launch

Boston, Mass., – November 8, 2016 – LaVoieHealthScience (LHS), an integrated strategic communications agency focused on health and life science, announced today it has won a MarCom Gold Award in the product launch category for the agency’s work on the Opn™ launch on behalf of its client, Oticon, an advanced audiology and hearing aid technology industry leader.

LHS developed a stratified media campaign for the Oticon Opn™ launch in the US and secured coverage on high-profile national outlets including the New York Times and USA Today as well as multiple local media outlets in targeted markets. The campaign employs a Harris Poll QuickQuery® and creates robust multimedia content such as an infographic and videos to raise awareness on hearing health, build recognition for Opn™, and increase engagement with prospective customers.

“The LHS team is honored to be acknowledged for our work on the Oticon product launch by MarCom Awards. Oticon Opn™ is a breakthrough hearing aid shown to improve speech understanding for people with hearing loss,” said Donna L. LaVoie, President and CEO of LaVoieHealthScience. “The launch of Opn™ is Oticon’s biggest product launch in more than a decade, and we are excited to be involved in bringing this technology to tens of millions of Americans affected by hearing loss.”

The MarCom Awards is a creative competition for any individual or company involved in the concept, writing and design of print, visual, audio and web materials and programs. Entries come from corporate marketing and communication departments, advertising agencies, PR firms, design shops, production companies and freelancers. The MarCom awards are one of the largest of its kind in the world with over 6,000 entries every year.

About LaVoieHealthScience

LaVoieHealthScience partners with leading life science brands to build value for their companies, attract capital, and reach key stakeholders through integrated communications and marketing. The firm provides strategic communications, investor relations and public relations to build recognition and increase sales and value for health science innovations to improve humankind. The agency has received 28 awards over the past seven years in recognition of the work it has done for its health and science industry-leading clients. The agency ranks among the 2016 Inc. 5000 list of fastest growing private companies.

###

Contact
Beth Kurth
Vice President, Investor Relations
bkurth@lavoiehealthscience.com
617-374-8800 x106

LaVoieHealthScience Celebrates 15 Years of Client Service to the Health & Science Industry By Supporting Advances in Cancer

LHS team fundraises at Jimmy Fund events and participates in their Strike Out for Cancer Initiative by donating to Dana-Farber Cancer Institute in Support of Oncology Research and Care

BOSTON, MASS. – October 26, 2016 – LaVoieHealthScience (LHS), an integrated strategic communications agency focused on health and life science, is celebrating its 15th anniversary in 2016. As such, the team participated in the annual WEEI/NESN Jimmy Fund Radio-Telethon and supported the Strike Out for Cancer initiative. “LHS works alongside health and science leaders to help build value for their innovations and, ultimately, benefit humankind,” said Donna L. LaVoie, President and CEO of LaVoieHealthScience. “We are proud to celebrate our 15th anniversary with volunteer work and donations in support of research and care advancement in oncology, a cause we deeply care about.”

LaVoieHealthScience Donating to the Jimmy Fund

LHS participated in the annual WEEI/NESN Jimmy Fund Radio-Telethon by staffing the phone bank and recording donations. The following day, LHS team members continued their efforts with in-park canister collections during a Red Sox game. During the two-day event, the Jimmy Fund raised more than $3.5 million with thousands supporting the lifesaving mission at Dana-Farber.

LHS also made a donation to the Dana-Farber Cancer Institute supporting the Strike Out for Cancer initiative.

About LaVoieHealthScience

LaVoieHealthScience partners with leading life science brands to build value for their companies, attract capital, and reach key stakeholders through integrated communications and marketing. The firm provides strategic communications, investor relations and public relations to build recognition and increase sales and value for health science innovations to improve humankind. The agency has received 28 awards over the past seven years in recognition of the work it has done for its health and science industry-leading clients. The agency ranks among the 2016 Inc. 5000 list of fastest growing private companies and among the Top 30 Independent Healthcare Firms as ranked by O’Dwyer’s PR.

###

Contact
Beth Kurth
Vice President
bkurth@lavoiehealthscience.com
617-374-8800  x106

Medicinal Genomics Uses DNA Sequencing on their Strands of Marijuana

Boston Business Journal

Medicinal Geonomics Woburn company applies DNA sequencing to budding marijuana industry

 

By: Jessica Bartlett

October 6, 2016

From Purple Haze to Orange Crush, the names given to different strains of marijuana are colorful, and largely just based on where the plant is grown or what people experience when smoking it.

But with medical marijuana’s recent legalization in many states, Woburn-based Medicinal Genomics Corporation is clearing the haze from the differences among different kinds of plants, offering genomics-based quality and strain identification testing for medical and recreational marijuana.

Medicinal Geonomics Lab Photo Woburn“We set out to ask, what questions can we answer with DNA?” said Kevin McKernan, chief scientific officer for Medicinal Genomics, which also offers genomics testing for patients. “The first thing that became apparent in the market is people are tired of not knowing what strain they are dealing with. People name the strains with esoteric and colorful names, but there is no guarantee of what you have.”

After offering a test version of the service to Colorado marijuana manufactures in April, the five-year-old company this week started offering genomics testing for marijuana growers across the country. Clients send DNA samples to the company and receive a partial genome sequencing of the plant, providing a fingerprint of each plant. That can help growers know which plants are psychoactive — containing the euphoric ingredient tetrahydrocannabinol — and which have high amounts of a compound known as cannabidiol that offers medicinal properties of the plant, without the ability to get someone high.

In the 25 states and the District of Columbia which have legalized medical marijuana, the market for genomics testing is wide open. Scientists now typically test only for contamination of plants.

But growers have started to sequencing their strains for intellectual property reasons, and also analyze the genetics to determine which plants are male and shouldn’t be planted (male plants pollinate, ruining an entire crop), and which ones are most productive. For consumers, genetic mapping can tell patients which strains are related, so they can effectively shop at dispensaries. In recreational pot markets, growers are using genetic testing as a branding tool.

McKernan says the size of the market is tough to gauge, but he says safety testing in the food industry — which typically captures 1-3 percent of the market — may be a good guide. If that same percentage holds true in cannabis, the market opportunity could be as much as $1 billion, given the estimated $20 billion to $40 billion market anticipated by 2020. McKernan argues it could be even larger if the company helps marijuana growers breed specific plants with specific properties such as a longer plant with tall stems for hemp fiber, or one with a lot of seeds to make oil.

“We think it will go beyond measuring the fingerprints,” McKernan said. “Traditional agriculture genomics is they began measuring … to select particular traits and could accelerate breeding programs.”

While Medicinal Genomics is growing the marijuana-testing side of the business, the 100-person company will recognize most of its 50-100 percent annual growth on the other side of the business that looks at patients’ genomes to determine the best treatments. Currently, the company is sequencing between 500 to 1,000 patients a month.

NewLink Receives Funds for Research on Ebola Vaccine V920

NewLink

endpoints news

Feds help NewLink, Merck out with some added cash for Ebola vaccine

 

By: Arsalan Arif

October 6, 2016

Two months after NewLink was forced to restructure and slash staff in the wake of a Phase III debacle on pancreatic cancer, the Ames, IA-based biotech and its Big Pharma partner Merck can celebrate some added federal research and manufacturing support for their Ebola vaccine.

BARDA — the Biomedical Advanced Research and Development Authority — is handing over $25 million in cash to back up work on V920. There’s another $51 million in added support if BARDA chooses to hand it over. The R&D ops group has already provided $76.8 million for this project, which was sped up considerably during a recent outbreak that has since burned out.

NewLink shares $NLNK surged 7% Wednesday on the news, part of an ongoing recovery that has helped the company’s stock climb back toward where it was trading when their Phase III flopped.

Ebola, though, is an ever present danger, and vaccine development is still underway at some of the majors, like J&J and GSK. Merck stepped in to partner with NewLink in late 2014, as headlines about the outbreak spread fear about the lethal virus. Last July the FDA handed the program a breakthrough therapy designation while the EU stepped up with a comparable inside track designation of its own.

“This new contract issued by BARDA will enable accelerated full-scale production of V920, once it is approved, and is a critical step in helping to make this vaccine available to the health care community as they work to control epidemics and protect medical workers and others at high risk,” said NewLink COO Thomas P. Monath in a prepared statement.

 

Fiercebiotech

Merck, NewLink nab up to $76M BARDA contract to back Ebola vaccine

 

By: Stacy Lawrence

October 5, 2016

Partners Merck ($MRK) and NewLink Genetics ($NLNK) have nabbed a $24.8 million contract to support the development of their Ebola vaccine. The candidate just won a breakthrough designation from the FDA and priority medicine status from the EMA in July, with an FDA submission expected next year.

The new grant brings the total invested into the Ebola vaccine candidate, rVSV∆G-ZEBOV GP (V920), by the Biomedical Advanced Research and Development Authority (BARDA) of the U.S. Department of Health and Human Services to more than $100 million. The award also includes another optional $51 million. The funding is slated to go to manufacturing facility readiness, manufacturing process qualification activities and clinical trials.

“This new contract issued by BARDA will enable accelerated full-scale production of V920, once it is approved, and is a critical step in helping to make this vaccine available to the health care community as they work to control epidemics and protect medical workers and others at high risk,” said Dr. Thomas Monath, CSO and COO of the NewLink Infectious Disease Division, in a statement.

Merck in-licensed the vaccine candidate from NewLink in late 2014, with the pharma gaining exclusive worldwide license to develop and market it. The pharma paid a $30 million upfront in October 2014 followed by a $20 million milestone in February 2015 for the start of the pivotal clinical trial. NewLink stands to receive escalating single-digit to double-digit royalties on sales of the Ebola vaccine.

The BARDA infusion goes to a subsidiary of NewLink to continue to support the development of V920. The candidate was originally in-licensed by NewLink from the Public Health Agency of Canada (PHAC).

Based on BARDA’s support, V920 advanced through at least 12 clinical trials, including Phase III, in less than two years. Merck isn’t alone among the big pharmas in the development of an Ebola vaccine; Johnson & Johnson ($JNJ) and GlaxoSmithKline ($GSK) are also among those working on one.

Small cap NewLink was up on the latest BARDA news to a market cap of more than $450 million; it hasn’t recovered from May when it was crushed on the news that its Phase III pancreatic cancer trial for vaccine algenpantucel-L failed to meet the primary endpoint.

 

LEO Pharma Expands Partnering Presence with LEO Science & Tech Hub in Boston

photo

the_boston_globe-svg

LEO Pharma grabs toehold in Cambridge

 

By: Robert Weisman

September 29, 2016

Denmark’s LEO Pharma is the latest European health care company to open an office in Cambridge’s Kendall Square, a global life sciences hub.

The company, owned by the LEO Foundation based in the Danish town of Ballerup, plans to announce Friday that it is establishing a local outpost to help invest a $22.5 million fund that will finance collaborations developing skin disease treatments.

Three executives at LEO Science & Tech Hub, an arm of LEO Pharma, will set up shop in Cambridge to vet potential partnerships in dermatology research in the Boston area and beyond. The office plans to make an unspecified number of investments — each between $5 million and $10 million — into alliances with partners making similar contributions.

“By creating alliances with industry and academia here in the region, we hope to change the treatment paradiam in dermatology and improve the quality of life of people with skin diseases,” Kim Kjoeller, executive vice president for global research and development at LEO Pharma, said in a statement.

b3b

Spotlight: Q&A with Michael Sierra, Vice President, LEO Science & Tech Hub

October 3, 2016

Spotlight: Q&A with Michael Sierra, Vice President, LEO Science & Tech Hub

Q: Can you give us a quick overview of LEO Science & Tech Hub?

The LEO Science & Tech Hub is the first dermatology-focused innovation center in Boston. The Hub will join forces with the life sciences community to advance the treatment of skin diseases. The unique structure of the Hub will allow for diverse partnerships with academic institutions, biotech companies and venture capitalists, making Boston a logical choice for its location.

Q: What are the Hub’s goals for the coming years?

Our ultimate goal is to pave the way for precision medicine within dermatology so patients can quickly be prescribed precisely the right treatment for them. This has been done already in monitoring heart disease and been shown to reduce the need for surgery. We want to apply this technology to dermatology to help people with skin diseases get the right diagnosis and treatment.Michael Sierra, VP, LEO Science & Tech Hub

It’s about empowering patients and improving their quality of life. And enabling both patients and doctors to monitor, diagnose and treat skin diseases in a more effective and less invasive way.

Our team wants to help academia validate novel targets using LEO Pharma’s disease models and gain access to innovations and technologies that are not currently publicly available. We will actively search for technology partners to solve existing challenges within LEO Pharma’s R&D and independent business unit, LEO Innovation Lab. And of course, we want to provide opportunities for seed investments and establish relationships with external talents at world-class academic and biotech institutions.

Q: How do you plan on achieving these goals?

We want to identify a molecular ‘fingerprint’ or imaging technology that—backed up by an ever-growing sophisticated data set—allows a patient to monitor treatment, predict flare ups and facilitate dialogue with their doctor. We will engage with life science innovators to explore fields such as non-invasive biomarkers, artificial intelligence and imaging technologies.

Q: What can the Hub offer collaborators?

We want to join forces with life science innovators in the U.S. to change the treatment paradigm for people with skin diseases and take the first steps toward applying precision medicine in dermatology. By offering our collaborators access to funding and a unique global network of dermatology expertise, we want to act as catalysts for innovation and help advance new science and technology.

LEO Pharma has experts within our field—a powerful team able to work in an agile way. The Hub has access to full deal-making capabilities and can provide support in terms of seed investments and co-development. Through our parent company, the Hub offers access to a global network of dermatology expertise. Collaborators can access LEO Pharma’s preclinical and clinical expertise as well as the digital healthcare expertise of LEO Innovation Lab. Also, the Hub has funding to co-invest $5-10 million per project to move them forward.

Q: What does the Hub aim to accomplish through these collaborations?LEO Pharma Skin Infographic

First of all, we are seeking new paths of innovation through collaborations, meaning that we are seeking early potential breakthrough science and technologies to be used within dermatology. Forming collaborations can further expand our already extensive global network to connect the dots and will definitely add a lot of expertise as well as financial support. And not to forget, we strive to improve the quality life. These collaborations will allow us to advance new technologies and science to the next stage.

Q: Can we talk a little about burden of skin diseases?

One in four people worldwide live with a skin disease. In the United States, more than 100 million people—one-third of the country’s population—now live with a skin disease. These millions of people and their families face many challenges in their everyday lives. For some, their greatest challenge may be finding a treatment that works to alleviate their symptoms. For others, it’s sticking to their treatment regimen. For others, the social stigma of having a skin disease will be the biggest factor impacting on their quality of life.

Q: What is your vision for standard care in skin diseases in the near future?

Our vision is enabling patients and doctors to monitor, diagnose and treat skin diseases more effectively and in a more user-friendly way. Let me give some examples of what we hope can become a reality.

Imagine if you could use your iPhone to help diagnose whether that strange-looking rash on your arm is in fact a skin disease. With just one click, the phone sends a snapshot to a cloud data platform that quickly analyses your skin using artificial intelligence. Or imagine that, instead of having to undergo an uncomfortable skin biopsy, you could sit comfortably while the doctor takes a picture of your skin and with the help of advanced data analysis can prescribe the right treatment for you.

Q: Why chose Boston?

Boston is the world’s pre-eminent biotech hub with an established innovation ecosystem. Local higher education institutes enjoy global recognition and have over the years sent tens of thousands of talents to advance scientific and technology research. Another reason that we decided to locate the Hub here is the mature biotech scene. Being the first dermatology hub in Boston, we need easy and quick access to resources so that we can focus more on science and technology. We want to join forces with these talents, academic research labs and utilize the existing resources to progress our initiatives in improving diagnosis and treatments in skin diseases.

Donna LaVoie to Deliver Workshop at BioPharm America on How and When to Form a Corporate Board

Boston – September 14, 2016 – Donna LaVoie, president and CEO of LaVoieHealthScience (LHS), an award winning strategic communications agency focused on health and life science, will be a featured speaker on Wednesday, September 14, at the BioPharm America’s 9th Annual International Partnering Conference to be held in Boston.

BioPharm America provides a unique venue for hundreds of the world’s most innovative leaders across the biotech, finance, and pharma industries to participate in high-level networking and partnering meetings.

LaVoie’s workshop, titled Corporate Governance: When to Build a Board and How to Select Your Members, is part of Biotech Startup Day, designed for emerging companies to explore leadership, operations and pathways to commercialization.

The presentation is focused on corporate governance, providing insight about the purpose of a board, the appropriate timing and insight into selecting the right members. As the CEO of a leading business and her background in life science, LaVoie will offer expert guidance on the importance of complimenting business fundamentals with scientific expertise, as well as the appropriate resources to ensure a strong board.

Produced by the EBD group, BioPharm America is an exclusive life science partnering event of the year, fostering the right partners to participate in pre-scheduled meetings, informal networking, and strategic panel discussions.

About LaVoieHealthScience

LaVoieHealthScience partners with leading life science brands to build value for their companies, attract capital, and reach key stakeholders through integrated communications and marketing. The firm provides strategic communications, investor relations and public relations to build recognition and increase sales and value for health science innovations to improve humankind. The agency has received 28 awards over the past seven years in recognition of the work it has done for its health and science industry-leading clients. The agency ranks among the 2016 Inc. 5000 list of fastest growing private companies.

###

Contact
Beth Kurth
Vice President, Investor Relations
bkurth@lavoiehealthscience.com
617-374-8800 x106

Big3Bio Spotlights Q&A with Ian Chan, CEO & Founder, Abpro

abpro logob3b

 

 

 

About Abpro
Abpro is an integrated life science company focused on industrial biochemistry. Through its DiversImmune™ platform, Abpro leverages synthetic biology and immunology to create novel biomolecules for use in research, diagnostics, animal health and therapeutics. Abpro’s platform has been validated by major pharmaceutical, biotechnology and academic labs around the world.

What was your inspiration for founding Abpro?

We wanted to save the time required to generate basic biomolecules, so that life science research can be accelerated so that treatments can be developed faster. We had been end-users of biomolecules before and many times you are just waiting around for several months for biomolecules before research can even be started.

diversimmune

Tell us about Abpro’s proprietary DiversImmune™ Platform.

Historically, generating biomolecules takes a very long time – from months to years. This is because it requires teams of highly skilled scientists working to find the exact conditions to generate each biomolecule one step at a time. The DiversImmune platform replaces the previously labor intensive steps with technology so that the entire process can be accelerated. Traditionally, antibodies can take up to twelve months to make, for example. With our platform, we have been able to reduce this to less than two months. We leverage massively parallel processes so that multiple steps can be run at the same time. We call this process industrial biochemistry because it replaces manual work with the latest technologies in immunology, next-generation sequencing and engineering.

Why do we hear “more shots on goal” with the Abpro platform?

Our platform allows scientists to design new products by allowing the rapid study of genes. Our Diversimmune platform allows the byproducts from the genes to be quickly created and studied so that new products can be created. Our platform creates “more shots on goal” since we are able to very rapidly create the test products that meet targeted endpoints.

What is synthetic biology, sounds like a contradiction in terms?

Synthetic biology is an application of engineering concepts on a broad scale to understand the complex world of biology in a more simple way. It allows biology to be used deliberately to create novel products.

What are the advantages of using Abpro antibodies?

In addition to more shots on goal, our platform creates biomolecules that are similar to the ones create in Nature. For example, in the case of antibodies, these generally have characteristics such as high binding, specificity and functionality. Our biomolecules, especially monoclonal antibodies, are engineered to be as close to the ones you would find in Nature as possible. These natural characteristics make them very appealing since they generally contain fewer side effects compared to artificially-made antibodies. Additionally, our platform is also much faster than competitive approaches.

Who are your current partners? Can you drop some names?

Some of our partners include Amgen, Genzyme, Merck, Pfizer and others. In addition, Abpro has collaborated with several academic research centers, including Harvard University, Massachusetts Institute of Technology and Stanford University and leading academic medical centers to include Massachusetts General Hospital and Brigham and Women’s Hospital.

What do you look for in your partners?

We generally look for partners that are at the forefront of research that have a track record of developing products that have the ability to improve living health, in the research, diagnostics and therapeutics industries. Our partners are global at this point and we are fortunate that they include some of the largest and most successful companies in the industry, such as top academic and research centers and Fortune 100 companies.

You’re often cited as a pioneer in industrial biochemistry. Would you please elaborate?

Industrial biochemistry is the application of synthetic biology and immunology to the life sciences industry so that novel products and treatments can be brought to patients faster. We focus the power of synthetic biology on the life sciences industry.

It sounds like your platform is giving Mother Nature an assist?abpro-ann-liu-l

Immuno-oncology is the fastest-growing category of mAb therapeutics entering clinical studies today and represent tremendous potential. These treatments stimulate Nature’s own immune system to fight cancer.

Immuno-oncology treatments have broad implications for treating disease:

  • We can create molecules that treat disease the way our natural immune system intended to, with better efficacy and lower side effects
  • New therapies can be created that were previously not available against diseases such as cancer

What are some of the goals you hope to achieve at Abpro? Your vision for the future?

Our vision is to be able to help usher in an era powered by biology with novel products that are developed faster and can benefit mankind. Biology is relevant in all aspects of society. By being able to understand biology faster, we can design new products and bring them to market in an accelerated manner. This includes treating disease, such as cancer, at a new level with cutting edge products.

Any final words?

We are excited about the current trends using antibodies to treat disease. There is real progress being made to help patients. We look forward to continuing to play a major role in the industry and helping our partners not only accelerate their research but to bring novel products that can improve living health to market.

 

Life Science Leader Features Stefan Weber, CEO of Newron Pharmaceuticals SpA, on Drug Company Discovery & Commercialization

newron-logo

lsl

Drug Company Discovery & Commercialization: An Election Year Analogy

stefanweberBy Stefan Weber, CEO and Executive Director, Newron Pharmaceuticals SpA

When smaller, boutique drug companies move from precommercial discovery to postcommercial marketing, they can experience a shock. Precommercial work is typically rigorous and controlled with trials conducted in sequential fashion and oversight done by recognized governing bodies. Of course there can be detours along the way, but generally speaking, the path itself is well-known. In contrast, postcommercial work expands the ecosystem and, therefore, brings with it an increasing number of participants, functions, relationships, and unknowns.

To continue reading this story, subscribe to Life Science Leader.